Counties entirely or partially within the district are Alachua, Baker, Bradford, Brevard, Clay, Duval, Flagler, Indian River, Lake, Marion, Nassau, Okeechobee, Orange, Osceola, Putnam, St. Johns, Seminole and Volusia.
The District operates and maintains nearly 90 major and minor water control structures, including three navigational locks and about 300 miles of levees and canals.
The District owns or manages 777,912 acres of land (through transfers, donations, fee-simple purchases and less-than-fee acquisitions). The majority of the property is open for the public to enjoy.